Études cliniques
Études chez l'humain pour évaluer la sécurité, l'efficacité et les dosages optimaux, souvent menées en plusieurs phases.
DATE
TITRE
PUBLICATION
Jan. 2023
Skin Test Institute report CTE419A/R
MyPureSkin
12-week anti-aging dietary supplement clinical study involving 43 female volunteers. Double-blind, placebo-controlled study evaluating the following benefits: hydration, firmness, elasticity, wrinkles, radiance and other parameters related to skin condition.
SEP 13, 2021
Biochemistry, Collagen Synthesis
StatPearls Publishing
Wu M, Cronin K, Crane JS. Biochemistry, Collagen Synthesis. 2021 Sep 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan--. PMID: 29939531
JAN 01, 2019
Oral Collagen Supplementation: A Systematic Review of Dermatological Applications
Journal of Drugs in Dermatology
Choi, F.D.; Sung, C.T.; Juhasz, M.L.; Mesinkovsk, N.A. Oral Collagen Supplementation: A Systematic Review of Dermatological Applications. J. Drugs. Dermatol. 2019, 18, 9--16.
JUL 01, 2012
Hyaluronic acid: A key molecule in skin aging
Dermato-Endocrinology
Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258. doi:10.4161/derm.21923
MAY 01, 1994
Age-dependent changes of hyaluronan in human skin
Journal of Investigative Dermatology
Meyer LJ, Stern R. Age-dependent changes of hyaluronan in human skin. J Invest Dermatol 1994; 102:385-9; PMID:8120424; http://dx.doi.org/10.1111/1523-1747.ep12371800
OCT 05, 2005
Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin
Archives of Dermatological Research
Barel, A., Calomme, M., Timchenko, A., De Paepe, K., Demeester, N., Rogiers, V., Clarys, P., & Vanden Berghe, D. (2005). Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Archives of dermatological research, 297(4), 147--153.
SEP 21, 2017
Improving Skin Hydration and Age-related Symptoms by Oral Administration of Wheat Glucosylceramides and Digalactosyl Diglycerides: A Human Clinical Study
Cosmetics
Bizot, V., Cestone, E., Michelotti, A., & Nobile, V. (2017). Improving skin hydration and age-related symptoms by oral administration of wheat glucosylceramides and digalactosyl diglycerides: A human clinical study. Cosmetics, 4(4), 37. https://doi.org/10.3390/cosmetics4040037
JUN 01, 2019
Evaluation of phenolic compounds, antioxidant and antiproliferative activities of 31 grape cultivars with different genotypes
Journal of Food Biochemistry
Xia, L., Xu, C., Huang, K., Lu, J., & Zhang, Y. (2019). Evaluation of phenolic compounds, antioxidant and antiproliferative activities of 31 grape cultivars with different genotypes. Journal of food biochemistry, 43(6), e12626. https://doi.org/10.1111/jfbc.12626
JUN 29, 2015
Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men
Clinical, Cosmetic and Investigational Dermatology
Costa, A., Pegas Pereira, E. S., Assumpção, E. C., Calixto Dos Santos, F. B., Ota, F. S., de Oliveira Pereira, M., Fidelis, M. C., Fávaro, R., Barros Langen, S. S., Favaro de Arruda, L. H., & Abildgaard, E. N. (2015). Assessment of clinical effects and safety of an oral supplement based on marine protein, vitamin C, grape seed extract, zinc, and tomato extract in the improvement of visible signs of skin aging in men. Clinical, cosmetic and investigational dermatology, 8, 319--328. https://doi.org/10.2147/CCID.S79447
AUG 12, 2017
The roles of vitamin C in skin health
Nutrients
Pullar J.M., Carr A.C., Vissers M.C.M. The roles of vitamin C in skin health. Nutrients. 2017; 9:866--892. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579659/
JUL 01, 2002
Protective effect of vitamin E on ultraviolet B light-induced damage in keratinocytes
Molecular Carcinogenesis
Maalouf S, El-Sabban M, Darwiche N, Gali-Muhtasib H. Protective effect of vitamin E on ultraviolet B light-induced damage in keratinocytes. Mol Carcinog. 2002;34:121--30.
JUL 10, 2014
Zinc therapy in dermatology: a review
Dermatology Research and Practice
Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Zinc therapy in dermatology: a review. Dermatol Res Pract. 2014;2014:709152. doi: 10.1155/2014/709152. Epub 2014 Jul 10. PMID: 25120566; PMCID: PMC4120804.
FEB 11, 2018
Zinc and Skin Disorders
Nutrients
Ogawa Y, Kinoshita M, Shimada S, Kawamura T. Zinc and Skin Disorders. Nutrients. 2018 Feb 11;10(2):199. doi: 10.3390/nu10020199. PMID: 29439479; PMCID: PMC5852775.
MAR 31, 2018
A Specific Melon Concentrate Exhibits Photoprotective Effects from Antioxidant Activity in Healthy Adults
Nutrients
Egoumenides L, Gauthier A, Barial S, Saby M, Orechenkoff C, Simoneau G, Carillon J. A Specific Melon Concentrate Exhibits Photoprotective Effects from Antioxidant Activity in Healthy Adults. Nutrients. 2018 Mar 31;10(4):437. doi: 10.3390/nu10040437. PMID: 29614719; PMCID: PMC5946222.
DEC 12, 2015
Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology
Journal of Medicinal Food
Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology. J Med Food. 2015 Dec;18(12):1340-8. doi: 10.1089/jmf.2015.0022. Epub 2015 Nov 12. PMID: 26561784; PMCID: PMC4685482.
JUL 11, 2011
Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women
Journal of Nutrition
Heinrich, U.; Moore, C.E.; De Spirt, S.; Tronnier, H.; Stahl,W. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women. J. Nutr. 2011, 141, 1202--1208.
APR 04, 2019
Therapeutic role of lipases and lipase inhibitors derived from natural resources for remedies against metabolic disorders and lifestyle diseases
South African Journal of Botany
A. Jawed, G. Singh, S. Kohli, A. Sumera, S. Haque, R. Prasad, D. Paul, Therapeutic role of lipases and lipase inhibitors derived from natural resources for remedies against metabolic disorders and lifestyle diseases, South African Journal of Botany, Volume 120, 2019, Pages 25-32, ISSN 0254-6299, https://doi.org/10.1016/j.sajb.2018.04.004.
JAN 01, 2001
Total triterpenic fraction of Centella asiatica in chronic venous insufficiency and in high perfusion microangiopathy
Angiology
L. Incandela, M.R. Cesarone, M. Cacchio, M.T. DeSanctis, C. Santavenere, and M.G. D'Auro,"Total triterpenic fraction of Centella asiatica in chronic venous insufficiency and in high perfusion microangiopathy,"Angiology, vol. 52, pp.9--13,2001.
JAN 01, 2022
Effects of the consumption of guarana on human health: A narrative review
Comprehensive Reviews in Food Science and Food Safety
Torres EAFS, Pinaffi-Langley ACDC, Figueira MS, Cordeiro KS, Negrão LD, Soares MJ, da Silva CP, Alfino MCZ, Sampaio GR, de Camargo AC. Effects of the consumption of guarana on human health: A narrative review. Compr Rev Food Sci Food Saf. 2022 Jan;21(1):272-295. doi: 10.1111/1541-4337.12862. Epub 2021 Nov 9. PMID: 34755935.
JUN 12, 2019
The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Frontiers in Pharmacology
Akbari M, Lankarani KB, Tabrizi R, Ghayour-Mobarhan M, Peymani P, Ferns G, Ghaderi A, Asemi Z. The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Pharmacol. 2019 Jun 12;10:649. doi: 10.3389/fphar.2019.00649. PMID: 31249528; PMCID: PMC6582779.
AUG 01, 2016
Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Journal of Medicinal Food
Daily, J. W., Yang, M., & Park, S. (2016). Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Journal of medicinal food, 19(8), 717--729. https://doi.org/10.1089/jmf.2016.3705
APR 01, 2002
Effect of vitamin E on plasma malondialdehyde, antioxidant enzyme levels and the rates of wound closures during wound healing in normal and diabetic rats
Asia Pacific Journal of Clinical Nutrition
Musalmah M, Fairuz AH, Gapor MT, Ngah WZ. Effect of vitamin E on plasma malondialdehyde, antioxidant enzyme levels and the rates of wound closures during wound healing in normal and diabetic rats. Asia Pac J Clin Nutr. 2002;11 Suppl 7:S448-451. (PubMed)
2012
Role of vitamin B6 in skin health and diseases
Wageningen Academic Publishers
Kato, Norihisa. (2012). Role of vitamin B6 in skin health and diseases. 10.3920/978-90-8686-729-5_4.
FEB 2015
A review of vitamin B12 in dermatology
American Journal of Clinical Dermatology
Brescoll J, Daveluy S. Am J Clin Dermatol. 2015 Feb;16(1):27-33. doi: 10.1007/s40257-014-0107-3. PMID: 25559140.
2019
The Role of Vitamins and Minerals in Hair Loss: A Review
Dermatology and Therapy
Almohanna HM, Ahmed AA, Tsatalis JP, Tosti A. Dermatol Ther (Heidelb). 2019;9(1):51-70. doi:10.1007/s13555-018-0278-6.
SEP 2012
Pantothenic acid based dietary supplement in subjects with acne
Journal of Cosmetics, Dermatological Sciences and Applications
Capodice JL. J Cosmet Dermatol Sci Appl. 2012;2:132–5.
JUL 10, 2014
Zinc therapy in dermatology: a review
Dermatology Research and Practice
Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Dermatol Res Pract. 2014;2014:709152. doi:10.1155/2014/709152.
FEB 11, 2018
Zinc and Skin Disorders
Nutrients
Ogawa Y, Kinoshita M, Shimada S, Kawamura T. Nutrients. 2018 Feb 11;10(2):199. doi: 10.3390/nu10020199.
NOV 2019
Brittle Nails: Pathogenesis, Clinical Signs and Treatment
Dermatology and Therapy
Chessa MA et al. Dermatol Ther (Heidelb). 2020 Feb;10(1):15-27. doi: 10.1007/s13555-019-00338-x.
AUG 2017
A Review of the Use of Biotin for Hair Loss
Skin Appendage Disorders
Patel DP, Swink SM, Castelo-Soccio L. Skin Appendage Disord. 2017 Aug;3(3):166-169. doi: 10.1159/000462981.
NOV 2021
Role of ingestible carotenoids in skin protection
Photodermatol Photoimmunol Photomed
Baswan SM, et al. Photodermatol Photoimmunol Photomed. 2021 Nov;37(6):490-504. doi: 10.1111/phpp.12690.
2016
UV-induced skin aging: DNA damage and oxidative stress
Stem Cells International
Panich U, et al. Ultraviolet radiation-induced skin aging: the role of DNA damage and oxidative stress. Stem Cells Int. 2016;2016:7370642.
SEP 13, 2021
Biochemistry, Collagen Synthesis
StatPearls Publishing
Wu M, Cronin K, Crane JS. Biochemistry, Collagen Synthesis. 2021 Sep 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 29939531.
JAN 2019
Oral Collagen Supplementation: A Systematic Review of Dermatological Applications
Journal of Drugs in Dermatology
Choi FD, Sung CT, Juhasz MLW, Mesinkovsk NA. J Drugs Dermatol. 2019;18(1):9–16.
2012
Hyaluronic acid: A key molecule in skin aging
Dermatoendocrinology
Papakonstantinou E, Roth M, Karakiulakis G. Dermatoendocrinol. 2012;4(3):253-258. doi:10.4161/derm.21923.
MAY 01, 1994
Age-dependent changes of hyaluronan in human skin
Journal of Investigative Dermatology
Meyer LJ, Stern R. J Invest Dermatol 1994; 102:385-9; PMID:8120424.
2013
Black pepper and health claims: a comprehensive treatise
Critical Reviews in Food Science and Nutrition
Butt MS et al. Crit Rev Food Sci Nutr. 2013;53(9):875-86. doi: 10.1080/10408398.2011.571799. PMID: 23768180.
MAY 1998
Influence of piperine on the pharmacokinetics of curcumin
Planta Medica
Shoba G et al. Planta Med. 1998 May;64(4):353-6. doi: 10.1055/s-2006-957450. PMID: 9619120.
2018
Potential role of coenzyme Q10 in health and disease conditions
Nutrition and Dietary Supplements
Rodick TC et al. Nutrition and Dietary Supplements. 2018;10:1-11.
2019
Coenzyme Q10: From bench to clinic in aging diseases
Critical Reviews in Food Science and Nutrition
Gutierrez-Mariscal FM, Yubero-Serrano EM, Villalba JM, Lopez-Miranda J. Crit. Rev. Food Sci. Nutr. 2019, 59, 2240–2257.
FEB 2000
Piperine increases plasma levels of coenzyme Q10
Journal of Nutritional Biochemistry
Badmaev V, Majeed M, Prakash L. J Nutr Biochem. 2000 Feb;11(2):109-13. doi: 10.1016/s0955-2863(99)00074-1. PMID: 10715596.
AUG 2017
The Roles of Vitamin C in Skin Health
Nutrients
Pullar JM, Carr AC, Vissers MCM. Nutrients. 2017; 9:866–892.
JUL 2002
Protective effect of vitamin E on ultraviolet B light-induced damage in keratinocytes
Molecular Carcinogenesis
Maalouf S, El-Sabban M, Darwiche N, Gali-Muhtasib H. Mol Carcinog. 2002;34:121–30.
2002
Effect of vitamin E on wound healing in normal and diabetic rats
Asia Pacific Journal of Clinical Nutrition
Musalmah M, Fairuz AH, Gapor MT, Ngah WZ. Asia Pac J Clin Nutr. 2002;11 Suppl 7:S448-451.
MAR 2018
Melon Concentrate Exhibits Photoprotective Effects in Healthy Adults
Nutrients
Egoumenides L, et al. Nutrients. 2018 Mar 31;10(4):437. doi: 10.3390/nu10040437.
APR 2017
Effect of rosmarinic acid and carnosic acid on AGEs formation in vitro
Food Chemistry
Ou J, et al. Food Chem. 2017 Apr 15;221:1057-1061.
FEB 2019
Phytochemicals Modulate Age-Related Phenotype of Skin Fibroblasts
Frontiers in Genetics
Sodagam L, et al. Front Genet. 2019 Feb 21;10:81. doi: 10.3389/fgene.2019.00081.
JUN 2020
Milk thistle and olive extract: sun-induced skin damage
Giornale Italiano di Dermatologia e Venereologia
Di Caprio R, et al. G Ital Dermatol Venereol. 2020 Jun;155(3):286-293. doi: 10.23736/S0392-0488.17.05726-1.